For the first time in ages, Marcy Pivin's really living.

Marcy had struggled with intractable depression for 15 years. Starting with a severe bout of post-partum depression after the birth of her first child, her condition worsened after the birth of her second child. Like many patients with depression, she developed resistance to some medications, while others were ineffective.

Marcy began to have suicidal thoughts.

In early 2004, Marcy and her husband heard about the Washington University's research into transcranial magnetic stimulation (TMS) at Barnes-Jewish Hospital.

TMS uses magnetic energy to stimulate the brain, resulting in enhanced mood for patients with major depression. TMS also shows promise for having potentially fewer side effects than traditional treatments, according to Keith Isenberg, MD, Washington University professor of psychiatry and director of ECT services at Barnes-Jewish Hospital.

"It is important for patients to have options for treatment. Through the team approach here, we are able to find a treatment which best serves our patients," says Dr. Isenberg.

Marcy was scheduled for 15 treatments, but noticed a change after only four. And, her apparent benefit has been sustained for more than six months.

"I am no longer in survival mode," she says. "I am actually living my life."

Once again, she revels in family life, instead of fighting feelings of isolation. She hopes to put depression behind her and live life to the fullest.